Posts tagged: biofilm infections

Ondine To Launch Ventilator-Associated Pneumonia (VAP) Photodisinfection Clinical Study

We are thrilled to announce that the FDA has approved a human clinical study to investigate the use of photodisinfection to prevent ventilator-associated pneumonia (VAP). VAP occurs when a lung infection develops in a patient ventilated with an endotracheal tube and continues to be the #1 cause of healthcare-associated infections in intensive care units. In the U.S alone, more than 1.3 million patients are mechanically ventilated every year. Of these patients, 10%-20% will develop ventilator-associated pneumonia, and up to half of them will die.

“A successful VAP study would represent a key step towards the commercialization of this new application of photodisinfection which utilizes Ondine’s patented technology and products…(our technology) has been proven to be highly effective at eliminating biofilms in ex vivo models, it is therefore ideally suited for the elimination of endotracheal tube biofilms resulting in the prevention of VAP” says Carolyn Cross, Chairman & CEO of Ondine.

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What Is A Biofilm?

In the past six years I’ve learned a lot about bugs. Microbes comprise 70% of all living organisms in the world. And we have ten times more bacteria than human cells. So why ponder these peculiar facts? In short, how we understand the myriad interactions between humans and microbes decides how we treat – or fail to treat – a range of human diseases.

My first unexpected foray into the pathology of bacterial disease started in 2005, as I became increasingly ill with an odd constellation of symptoms that eluded doctors. Looking back, it seems possible I visited every medical specialty in western medicine! My shortness of breath, fatigue, cardiovascular troubles and neck pains puzzled my PCP, ENTs, orthopedic surgeons, chiropractors, a physiatrist and an interventional radiologist. And that’s not the complete list. I knew I wasn’t crazy as my health spiraled downward into an indescribable hell.

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