Posts tagged: Periowave

How does Photodisinfection Work?

Photodisinfection is a topical, non-antibiotic antimicrobial therapy that destroys a broad spectrum of pathogens including fungi, bacteria and virus without damaging human tissue. Unlike antibiotics, Photodisinfection selectively kills virulence factors such as the endotoxins and exotoxins produced by pathogens, leading to a clinically observable anti-inflammatory effect. The treatment process takes only minutes, making it over 1,000 times more effective at biofilm killing than antibiotics.

Photodisinfection is a minimally invasive non-thermal therapy involving the light activation of a photosensitizer to eliminate topical infections in a highly targeted approach. Photodisinfection has been proven to be safe and effective in other applications such as for the dental, sinusitis and hospital acquired infection prevention markets. In dentistry, Photodisinfection has been proven to be highly effective for the treatment of caries, endodontics, restorative dentistry, periodontitis, peri-implantitis and halitosis. Many new applications of Photodisinfection are now under development.

The Photodisinfection Process: Instant Antimicrobial Therapy

Apply Photosensitizer to Infection Site & Illuminate with Appropriate Wavelength for Several Minutes

A photosensitizing solution is applied to the treatment site where the photosensitizer molecules preferentially bind to the targeted microbes.  The photosensitizer molecules are inactive at this stage.  A light of a specific wavelength and intensity illuminates the treatment site and a photocatalytic reaction occurs.  The wavelength is carefully chosen to maximize absorption of light energy by the photosensitizer.

This 2 step procedure results in the destruction of the targeted microbes and their virulence factors without damaging host cells.  This reaction involves the formation of short-lived, highly reactive free-radical oxygen species.  These radicals cause a physical disruption of the microbial cell membrane through oxidative reactions, resulting in immediate rupture and destruction of the cell.  This process occurs in seconds with total kills completed in minutes.

The Photodisinfection process has also been shown to eliminate a multitude of virulence factors, unlike antibiotics. When the light isremoved, the photocatalytic reaction ceases along with all antimicrobial action. Photodisinfection does not promote the development of resistance.

The Photodisinfection process is both pain-free and stress-free due to lack of side-effects or damage to human tissue.

Source: Eastman Dental Institute, UK

Study Using Periowave™ Shows Rapid Resolution Of Aggressive Periodontitis

We’re pleased to announce today that the results of a study involving antimicrobial Photodynamic Therapy (aPDT), or Photodisinfection, were presented at the 13th International Photodynamic Association World Congress. This study, conducted by Dr. Veronique Benhamou, evaluated the use of the Periowave™ Photodisinfection System in the treatment of an aggressive case of periodontitis.

The current standard of care for aggressive periodontitis involves scaling and root planing in conjunction with antibiotic therapy. The subject of this study received scaling and root planing followed by aPDT (PeriowaveTM) in place of any antibiotic therapy.  This protocol produced rapid, clinically significant results and no adverse events were reported.  The significance of the results was confirmed through standard clinical tests and x-rays.

Periowave™ is a painless, non-invasive procedure that can significantly improve treatment outcomes when added to scaling and root planing.

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Ondine CEO, Carolyn Cross, Inducted Onto The Board of the International Photodynamic Association

“We have spent the last 70 years using and misusing antibiotics to treat and prevent common infectious diseases…It is therefore imperative that non-antibiotic solutions to fight infections are developed in order to preserve the next generation of effective medicine.”

Carolyn Cross Inducted Onto Board of IPA

Our CEO has done it again. Two weeks after being featured in the Vancouver Sun Newspaper, Ms. Cross has now been inducted onto the Board of the International Photodynamic Association (IPA). Founded in 1986, the IPA brings together the most distinguished international clinicians and scientists involved in researching and developing photodynamic therapy. Ms. Cross will help raise awareness about the benefits of this technology and help bring it to the forefront of medicine.

We are very pleased to share this announcement with all of you today. Ms. Cross has been with Ondine for over a decade and was one of the initial founders and financial supporters of our company. Under her leadership, Ondine has developed a rapid R & D program and is now seen as one of the world’s most renowned group of experts on photodynamic therapy and photodisinfection. Read more »

Ondine’s 100th Post – An Exciting Blogging Milestone!

Today, we celebrate our first blogging milestone – our 100th post. It’s incredible to see how far we have come, and exciting to imagine where we soon will be. You, the readers and followers of Ondine’s blogs, have played the central role in getting us here; your encouraging words, insightful comments, and guest blog posts have helped us tremendously throughout this process. Thank you so much.

Our goal has always been to make important points in bite-sized, digestible sound bites for today’s fast paced world. Our first one hundred posts have helped lay the foundation for this, and our next steps involve creating more engaging, relevant and compelling content. This will come in the form of videos, graphics, testimonials and case studies from the field.

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Ondine Chairman & CEO, Carolyn Cross, Featured In Vancouver Sun Newspaper

Carolyn Cross, Chairman & CEO of Ondine Biomedical Inc, understands too well the importance of supporting women in business.  This week, the Vancouver Sun Newspaper highlighted her involvement & support for this week’s Women Presidents’ Organization (WPO) International Conference. This is a unique event that connects highly successful women from around the world in promoting the advancement of women across all industries. The WPO is an exclusive membership organization for women presidents of multimillion-dollar companies. Collectively, members of the WPO have 24,000 years in business, generate $14 billion in annual revenues, and employ 105,000 employees.

Carolyn Cross, Chairman & CEO of Ondine Biomedical Inc, was featured in today's Vancouver Sun Newspaper

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